AmplideX® PCR/CE FMR1:

AmplideX PCR/CE FMR1 is an in vitro diagnostic (IVD) kit for use in clinical laboratories in the detection of CGG repeats in fragile X mental retardation (FMR1) gene. The kit is intended to aid in the diagnosis of fragile X syndrome and fragile X associated disorders, e.g. tremor and ataxia syndrome (FX-TAS) and primary ovarian insufficiency (FXPOI), through determination of CGG repeat length up to 200 CGG and detection of alleles greater than 200 CGG. The kit provides a PCR-only approach based on Triplet Repeat Primed PCR (TP-PCR) design to reliably amplify and detect all alleles including Full Mutations.



AmplideX® mPCR FMR1:

The AmplideX mPCR FMR1 Kit employs an innovative PCR-only approach for the detection of methylation status in the FMR1 gene. These reagents determine the extent of methylation of each individual allele in both male and female samples, and thus eliminate the need to run tedious and time consuming Southern blots.


AmplideX® mPCR FMR1 Kit*:

The AmplideX mPCR FMR1 Kit provides intra-assay and allele-specific methylation quantification consistent with the Southern blot.


AmplideX® FMR1 Controls:

The AmplideX FMR1 Controls are proprietary mixtures of genomic DNA containing multiple alleles. These well-characterized controls can be used as process or batch controls covering multiple size ranges and different methylation states in the FMR1 gene.