The MILLIPLEX® portfolio of immunoassays is the largest portfolio of multiplex biomarker assays based on Luminex® xMAP® technology, offering consistent, high-quality results, so that you can do your best work while saving time, labor and costs.

Merck’s menu of metabolic and endocrine enzyme-linked immunosorbent assay provides end-users with access to a consistent and reliable method of investigating metabolic disease states or defining outcomes within toxicological studies during drug development. Choose from over 1,800 ELISAs.

Providing highly cited primary and secondary antibodies, we have you covered for your ELISA, western blot, immunohistochemistry or other assay needs from brands you know and trust; including Sigma-Aldrich, Millipore, Upstate, Chemicon, and Calbiochem.

With a complete portfolio of Western Blotting reagents and consumables including Immobilon® Block, Immobilon® Signal Enhancers, Immobilon® HRP Substrate for different sensitivities, as well as a wide range of Western Blotting PVDF Immobilon® Membrane in Roll, Pre-cut and Immobilon® Now newly launched Pre-cut roll, Merck’s optimized tools will help you achieve optimized results.

Whether you need ultra-sensitive detection from a Single Molecule Counter™ (SMC) assay, robust ELISAs, or rich multiplex profiling data using Luminex® xMAP® technology, Merck can help you get data you can trust out of each sample with minimal repetition enabling you to make the best next-step decisions. Products include:

• MagPix
• Luminex 200
• FlexMap 3D.

Cell culture is fundamental to life science research in universities, biotechnology, pharmaceuticals, and industry. Whether your goal is to establish relevant cell models to answer research questions or to produce recombinant proteins or virus particles, Merck has everything you need to keep your tissue culture room thriving. A complete portfolio offers plenty of choices for quality essentials from fetal bovine serum (FBS), culture media, supplements, and cryopreservation reagents to filtration units, general labware, and specialty cultureware.

Merck is a leader in filtration with innovations such as Millex® filters- the first disposable syringe filter devices; the iconic Stericup® filter units; and specialty membranes and filter devices. Researchers widely specify Millipore® filters when standardizing protocols. We provide broad range of Millex syringe filters, membrane filters, glass filter holders and other laboratory filtration products.

A comprehensive offering of protein preparation products provides gentle extraction, high-yield isolation and purification, and application-verified detection tools for techniques like electrophoresis and Western blot, ELISA, multiplex, and mass spectrometry.

Sigma Aldrich Life Science provides tools for every stage of the molecular biology workflow: Nucleic Acid Extraction, PCR, qPCR, rt-qPCR including Custom Oligos and Dual Labelled Probes etc.

The new Milli-Q® EQ 7000 water purification system purifies your pure water to ultrapure (Type 1) water, readily available for a broad range of applications. This configuration allows a full remote installation of the solution.

An intelligent and intuitive ultrapure water solution, the Milli-Q IQ 7000 is designed to make your work as pleasant and comfortable as possible in order to maximize lab productivity. Its breakthrough ergonomic design and powerful purification media ensure consistent production of superior-quality ultrapure water.

A fully-integrated water purification system with the ultimate lab water solution, the Milli-Q IQ 7003/05/10/15 provides superior quality Type 1 & Type 2 water directly from tap water.

Laboratories performing trace analyses need a reliable source of ultrapure water with consistently low elemental concentrations. When combined with a Milli-Q® IQ 7000 or Milli-Q® IQ 7003/05/10/15 water purification system, the Milli-Q® IQ Element purification and dispensing unit delivers analytical-grade ultrapure water that is suitable for trace and ultra-trace elemental analyses, including ICP-MS, GF-AAS and trace IC.

At the heat of your total pure water solution, the Milli-Q HX 7000 system serves as the nerve center for the entire water purification chain and provides total control of all functions, operating parameters and standard accessory components. Milli-Q HX systems compromise several water purification technologies, including complete pretreatment; advanced reserve osmosis (RO) and Evolutive Reject Adjustment (ERA™) water usage using quality optimization; Elix® electro-deionization (EDI) technology; and treatment by bactericidal UV lamp.

Purify, store, distribute, monitor and control your Type 2 waters entirely from the new Milli-Q® HX 7000 SD series of systems. Milli-Q HX 7000 SD all-in-one water purification systems are designed to deliver the highest quality of pure water in a complete, compact, and fully-customizable format. From a single laboratory to an entire building floor, the Milli-Q HX 7000 SD range has the capacity to purify up to 3000 L/day from tap water, reliably feeding all of your Type 2 water needs.

The Milli-Q® HR 7000 series of connected, high-throughput systems are designed to deliver a powerful, versatile and modern central pure water solution. From a single laboratory to an entire research facility, the Milli-Q® HR 7000 range has the capacity to purify up to 13,000 L/day from tap water, reliably feeding all your type 3 water needs. This includes taps on benches, instruments, point-of-use polishers, and ultrapure water purification systems.

Milli-Q® CLX 7000 connected purification systems provide an economical and reliable high-performance solution for clinical analyzers with pure water needs up to 3000L daily. Water produced complies with the Clinical & Laboratory Standards Institute® (CLSI) guideline for clinical lab reagent water (CLRW). It delivers consistent CLRW quality water, supports full data traceability, and promotes remote service and monitoring capabilities.

For bioburden testing in the pharmaceutical and cosmetics industries, Merck provides a complete portfolio of products and services designed to ensure microbiologically safe drugs and cosmetics. Merck’s products range from traditional to rapid and are based on proven technologies such as membrane filtration and fluorescence-based, non-destructive detection.

Merck’s traditional dehydrated culture media are based on a unique granulation technology. This ensures that products provide maximum convenience and safety, while meeting the highest industry performance standards as described in ISO 11133.

Merck’s ready-to-use liquid and solid (agar) media cover all the areas in pharmaceutical and cosmetics manufacturing that require microbiological testing or monitoring. The convenient and industry-tailored range of ready-to-use media come in a large variety of formats, formulations and sizes. Merck offers all-purpose products and selective culture media for very specific applications or instruments, as part of user-friendly and reliable solutions that make it easier for you to comply with your regulatory environment while improving workflow and productivity.

For over 40 years, Merck have been the leaders of the field of sterility testing providing the highest quality products and defining the path forward. In 1974, Merck were the first to market the Steritest™ closed filtration device. Since then, Merck have been instrumental in raising industry standards by reducing the risk of false positive and negative results, increasing reliability and improving workflow for lab technicians around the world.

Environmental monitoring is essential in today’s pharmaceutical and cosmetics industries. It supports in producing safe products in accordance with international standards and guidelines and helps to prevent the release of potentially contaminated products. Merck’s complete portfolio for environmental monitoring solutions covers:

• Active Air Monitoring
• Media for Active Air Monitoring
• Passive Air Monitoring
• Surface & Personnel Monitoring
• Environmental Monitoring in Isolators

In the pharmaceutical industry, pyrogen detection is mandatory to avoid the life-threatening fever reactions that can be induced by both microbial and non-microbial substances. Merck provides two MAT systems for the detection of a broad spectrum of Pyrogens:

• PyroDetect: The PyroDetect System was the first Monocyte Activation Test (MAT) kit available on the market. Merck’s PyroDetect system uses cryoblood (frozen human whole blood) as a source of monocytes and interleukin-1β as a read-out in the ELISA.
• PyroMAT: The Merck PyroMAT™ kit for pyrogen detection has distinct advantages over the current pyrogen testing methods.

Rapid microbiological detection solutions from Merck for bioburden testing effectively address the diverse contamination issues which face the pharmaceutical, cosmetics, food, beverages and municipal/environmental water industries every day. Innovative rapid technologies provide several advantages over classical culture-based methods: earlier results, increased assay sensitivity, ease-of-use, excellent accuracy and reliability.

Merck’s traditional dehydrated culture media are based on a superior granulation technology, which guarantees that our products provide maximum convenience and safety, while meeting the highest industry performance standards.

Microbial monitoring of food and beverage production plants is an important part of the HACCP principles to prevent food contaminations. Ready-to-use liquid and solid culture media from Merck are adapted to your decision criteria, from raw material qualification to finished product testing.

Environmental monitoring is essential in today’s industries. It not only avoids risks to consumers and producers, but also saves time and reduces costs. Merck provides a complete solution to you stay on the safe side. With high-quality products, excellent service and professional expertise, we provide more safety than meets the eye.

In sensitive industries like food and beverage production, detecting pathogens or, spoilage microorganisms can become a matter of urgency – to ensure consumer safety, avoid damage to your brands and minimize the associated costs. As an expert in these fields, Merck offers dependable, high-quality packages for all your food testing requirements. Benefit from our smart and convenient solutions to optimize your processes.

What if you could use fewer handling steps for your indicator organism testing, without compromising your results? Enumeration and detection of microbial contamination in food and beverage products is key but can be time consuming and complex. Streamline your workflow by trying Merck’s new color-coded MC-Media Pad® for rapid and convenient microbial testing.

For bioburden testing (including microbial limit testing) of non-sterile raw materials, water and finished products, Merck provides all the culture media required to detect viable aerobic microorganisms. The ready–to-use solid and liquid media are prepared according to the corresponding, harmonized standards of the European, US and Japanese Pharmacopeias.

Merck provides a complete portfolio of ready-to-use (RTU) culture media for microbiological bioburden testing. Culture media based on Casein Soy Bean Digest or Sabouraud Dextrose are recommended for the microbial enumeration tests TAMC (total aerobic microbial count) and TYMC (total yeast/molds count). Specialized culture media are available for the detection of specified aerobic microorganisms.

Merck offers a comprehensive portfolio of environmental monitoring solutions that covers:

• Active Air Monitoring
• Passive Air Monitoring
• Surface & Personnel Monitoring
• Particle Counting

Dehydrated raw materials, such as peptones, agar-agar and extracts, as well as supplements form part of Merck’s extensive portfolio of culture media products for industrial microbiology. Merck’s extensive range of quality controlled culture media ingredients allows manufacturers to produce reliable and user friendly products.

What if you could use fewer handling steps for your indicator organism testing, without compromising your results? Enumeration and detection of microbial contamination in food and beverage products is key but can be time consuming and complex. Streamline your workflow by trying Merck’s new color-coded MC-Media Pad® for rapid and convenient microbial testing.

The Integritest® 5 is an easy-to-use, portable, and fully-automated instrument that verifies the integrity of filters or processing equipment. MilliporeSigma introduced the first commercial automated integrity test instrument more than 25 years ago; our latest model now incorporates an improved algorithm to simplify test creation and accelerate test completion.

When it comes to your beverage process, you need comprehensive microbial management to produce high quality beverages without compromising flavor, consistency, or safety. Merck gives you the proven tools, technologies, and expertise to optimize your process performance, monitor product safety, and maintain product quality while meeting regulatory compliance.

Merck offers process solutions drawn from over 40 years of experience working closely with the most successful drug manufacturers in the world to ensure successful and robust clarification.

With Merck as your sterile filtration partner, you will have the peace of mind that comes from working with the industry leader that has over 50 years of expertise in sterile filtration and market leading products including Aervent® (PTFE), Durapore® (PVDF) and Millipore Express® (PES) membranes. Combined, Merck’s membranes have processed billions of sterile doses.

Merck has almost 40 years of experience with the most successful drug manufacturers in the world, helping them to ensure successful and robust ultrafiltration processes.

From early phase development, to large scale production, vaccine manufacturers are concerned with balancing speed to market and cost containment, while maintaining product safety. Merck’s process development engineers, regulatory experts and comprehensive portfolio of products and services can help you meet your process goals and many process challenges.

Viral safety is a critical aspect of biopharmaceutical/biologics production and relies on the well-established principles of “prevent, detect and remove” to assure drug safety for patients. Merck is your trusted partner with experience in all aspects of viral safety assurance enabling you to accelerate your drug development process and providing you with peace of mind.